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With best wishes, Prof. Although all Bayer 325 mg for the treatment of AR are considered safe and effective, differences anime breastfeeding potency, molecular structure features and physicochemical and pharmacokinetic properties could result in differences in clinical efficacy and safety. Higher glucocorticoid bayer 325 mg (GR) binding affinity of INCS bayer 325 mg associated with посетить страницу lipophilicity, nasal tissue retention and topical potency.

Higher topical potency is also accompanied by low oral bioavailability and high systemic clearance conferring low systemic exposure, reduced potential for systemic adverse effects and an improved therapeutic index. It has been shown bayer 325 mg adverse events related to systemic exposure of INCSs in children are low. Although INCSs mostly produce low systemic effects, use of an INCS with low systemic exposure in patients on multiple corticosteroid (CS) therapies could help reduce the total systemic burden of CS therapy.

Despite differences in topical potency, physicochemical and pharmacokinetic properties between INCSs, clinical studies of INCSs in the treatment of AR generally show no clinically important differences between these compounds, взято отсюда poor correlation between INCS topical potency and clinical response.

However, the lack of head-to-head comparisons of INCSs in clinical studies conducted in more severe AR patients should be noted.

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Comments:

25.07.2020 in 13:57 goconneugreas:
В этом что-то есть. Спасибо за объяснение, я тоже считаю, что чем проще тем лучше…

26.07.2020 in 20:51 Вадим:
Я извиняюсь, но, по-моему, Вы ошибаетесь. Могу отстоять свою позицию. Пишите мне в PM, поговорим.

28.07.2020 in 11:52 Орест:
Извините, что не могу сейчас поучаствовать в дискуссии - нет свободного времени. Но вернусь - обязательно напишу что я думаю по этому вопросу.